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Multiple Choice
Which of the following substances is responsible for limiting a platelet plug to the immediate area of damage?
A
thromboxane A2
B
serotonin
C
adenosine diphosphate
D
prostacyclin
Verified step by step guidance
1
Understand the role of platelet plugs in hemostasis: Platelet plugs are crucial for stopping bleeding by forming a temporary seal at the site of blood vessel injury.
Identify the substances involved in platelet plug formation: Thromboxane A2, serotonin, and adenosine diphosphate (ADP) are all involved in promoting platelet aggregation and vasoconstriction.
Recognize the function of prostacyclin: Prostacyclin is a substance produced by the endothelial cells lining blood vessels. It acts as a vasodilator and inhibits platelet aggregation, thus preventing the spread of the platelet plug beyond the site of injury.
Consider the balance between pro-aggregatory and anti-aggregatory factors: While thromboxane A2, serotonin, and ADP promote platelet aggregation, prostacyclin serves to limit this aggregation to the area of damage.
Conclude that prostacyclin is responsible for limiting the platelet plug to the immediate area of damage by counteracting the effects of the other substances involved in platelet aggregation.