Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.
b. Using the new strand that results from this mutation, write the order of bases in the altered mRNA.

Question

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.

b. Using the new strand that results from this mutation, write the order of bases in the altered mRNA.

Accepted Answer

All right. Hello everyone. So this question says to consider the DNA section shown below. Suppose that a point mutation occurred when the first base in the parent chain, thymine is replaced by cytosine, write the sequence of bases in the altered MNA using the new DNA strand resulting from this mutation. All right. So for this question, it's important to recognize that our answer is supposed to take into account this mutation and the sequence that's given is written before the mutation. So with the correct sequence. So before we go ahead and talking, before we go ahead and talk about finding the correct MRN a sequence, let's go ahead and change our DNA sequence to account for the mutation. So first and foremost, it says here that in the parent's chain, we have thymine replaced by cytosine. So if I write on the bottom here, this new parent chain that first nucleotide should be cytosine instead of thymine, but the rest of the sequence should remain the same since there's no mention of any other mutations. And so the new strand that's resulting after this mutation is going to base pair with the mutated cytosine recall that in the context of DNA, we have adenine pairing with thymine and vice versa, and cytosine pairing with guanine and vice versa. So in this new, new strand, right, the first nucleotide of it would be guanine pairing with the new cytosine in the parent strand. Though the rest of it should remain the same because once again, our other nucleotides have not changed. And so now that we've accounted for the mutation, let's go ahead and talking about, go ahead and talk about finding the new MRN A now because we have both strands of DNA visible. Here. There are two different ways to go about finding the MRN A. The first is to go ahead and use our complementary base pairing rules to figure out each nucleotide of the MRNA by finding what's complimentary to the new strand. The difference however, is that thymine is not found in RN A, which means that Adenine would instead pair with uracil and vice versa. But because we are able to see the parent chain that itself is complementary to the new strand, all we could do as well is copy the parent strand and replace thymine with uracil whenever visible. So for example, this new parent chain is CTCGTA A, I could copy this as the MRNA by replacing my two thymine with Uil. So that gives me CUC GGU A AG. And if I just go ahead and compare this to the new strand, I would see that this is also perfectly complementary to it. And so here we have our correct answer and there you have it. So with that being said, thank you so very much for watching. And I hope you found this helpful.

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.
b. Using the new strand that results from this mutation, write the order of bases in the altered mRNA.

Verified video answer for a similar problem:

Key Concepts

DNA Mutation

Transcription

Base Pairing Rules

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.b. Using the new strand that results from this mutation, write the order of bases in the altered mRNA.

Verified video answer for a similar problem:

Key Concepts

DNA Mutation

Transcription

Base Pairing Rules

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.
b. Using the new strand that results from this mutation, write the order of bases in the altered mRNA.