Skip to main content
Pearson+ LogoPearson+ Logo
Ch.10 Proteins Workers of the Cell
Frost - General, Organic and Biological Chemistry 4th Edition
Frost4th EditionGeneral, Organic and Biological ChemistryISBN: 9780134988696Not the one you use?Change textbook
Chapter 6, Problem 54a

Indicate whether each of the following describes a competitive or a noncompetitive inhibitor.
a. The structure of the inhibitor is similar to that of the substrate.

Verified step by step guidance
1
Understand the difference between competitive and noncompetitive inhibitors: A competitive inhibitor competes with the substrate for binding to the active site of the enzyme because its structure is similar to the substrate. A noncompetitive inhibitor binds to a different site on the enzyme (not the active site) and changes the enzyme's shape, reducing its activity regardless of substrate binding.
Analyze the statement: 'The structure of the inhibitor is similar to that of the substrate.'
Recognize that if the inhibitor's structure is similar to the substrate, it is likely to compete with the substrate for the active site of the enzyme.
Conclude that this description aligns with the characteristics of a competitive inhibitor.
Label the inhibitor described in the problem as a competitive inhibitor based on the reasoning above.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above.
Video duration:
3m
Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Competitive Inhibition

Competitive inhibition occurs when an inhibitor molecule resembles the substrate and competes for binding to the active site of an enzyme. This type of inhibition can be overcome by increasing the concentration of the substrate, as more substrate molecules can outcompete the inhibitor for the active site.
Recommended video:
Guided course
1:19
Enzyme Inhibition Concept 1

Noncompetitive Inhibition

Noncompetitive inhibition happens when an inhibitor binds to an enzyme at a site other than the active site, altering the enzyme's function regardless of substrate concentration. This means that increasing substrate levels does not affect the inhibitor's ability to reduce the enzyme's activity, as the inhibitor can bind to both the enzyme and the enzyme-substrate complex.
Recommended video:
Guided course
1:19
Enzyme Inhibition Concept 1

Enzyme-Substrate Complex

The enzyme-substrate complex is formed when a substrate molecule binds to the active site of an enzyme, facilitating the chemical reaction. Understanding this complex is crucial for distinguishing between competitive and noncompetitive inhibition, as the binding dynamics directly influence enzyme activity and reaction rates.
Recommended video:
Guided course
2:32
Enzyme-Substrate Complex Concept 1