Epistatic gene interaction results in a modification of the F₂ dihybrid ratio.
What is the expected F₂ ratio?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Epistasis and Complementation
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
A cross of white plants and red plants was performed. Using the F2 phenotypic ratio data below, determine what form of gene interaction is taking place.

A
Dominant Epistasis
B
Recessive Epistasis
C
Suppressors
D
Complementary Gene Action

1
Examine the phenotypic ratio of the F2 generation. The data shows 1125 red offspring and 875 white offspring.
Calculate the total number of offspring by adding the number of red and white offspring: 1125 + 875.
Determine the phenotypic ratio by dividing the number of each phenotype by the total number of offspring. This will help identify the pattern of inheritance.
Consider the possible gene interactions listed: Dominant Epistasis, Recessive Epistasis, Suppressors, and Complementary Gene Action. Complementary Gene Action often results in a 9:7 ratio, which is close to the observed ratio.
Conclude that the observed phenotypic ratio suggests Complementary Gene Action, where two genes interact to produce a phenotype, and both must be present for the red color to appear.
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Epistasis and Complementation practice set
