When performing a complementation test, how do you know if two mutations complement?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Epistasis and Complementation
Struggling with Genetics?
Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
In the rare Bombay phenotype, a mutation in a second gene can control an individual's what?
A
Hair color
B
Height
C
Blood type
D
Skin color

1
Understand the context of the Bombay phenotype: It is a rare genetic condition that affects blood type determination.
Recognize that the Bombay phenotype involves a mutation in the FUT1 gene, which is responsible for the production of the H antigen on red blood cells.
Note that the H antigen is a precursor for the A and B antigens. Without the H antigen, the A and B antigens cannot be formed, leading to the Bombay phenotype.
Identify that individuals with the Bombay phenotype will test as blood type O in standard blood typing tests, regardless of their actual ABO genotype.
Conclude that the mutation in the second gene (FUT1) controls the expression of blood type, not hair color, height, or skin color.
Related Videos
Related Practice
Multiple Choice
Epistasis and Complementation practice set
