In this chapter, we focused on the translation of mRNA i...

Question

In this chapter, we focused on the translation of mRNA into proteins as well as on protein structure and function. Along the way, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations in the chapter, what answers would you propose to the following fundamental questions:

What experimentally derived information led to Holley's proposal of the two-dimensional cloverleaf model of tRNA?

Accepted Answer

Hi, everybody. Let's take a look at this practice problem together which of the following statements about transfer rnatrn A is true. Recall that TRN A is an adapter molecule and its role is to transport the correct amino acid to the ribosome during translation. And now that's when polypeptides are being formed and amino acids are being added on. So let's take a look at our options. We've got a TRN A is a type of messenger RN A that carries genetic information from DNA to the ribosome. So this is false. This is describing the role of messenger RN am RN A. So A is not correct. Then we've got option BT RN A contains the genetic code for a specific amino acid. This is not a function of TRN A. Again, MRN A contains the genetic code. So B is also incorrect. Option C is TRN A is involved in the process of DNA replication. Now we know this is false. Remember, trn A is involved in translation. Therefore, the answer must be ad trn A has a unique cloverleaf structure with an anti codon sequence that binds to MRN A. This is the correct answer. The anti codon sequence of the TRN A corresponds with the matching code on sequence of the MRN A. So D is the correct answer. All right, everyone. I hope you found this helpful and I'll see you soon for the next practice problem.

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