Genomic DNA from a mouse is isolated, fragmented, and denatured into single strands. It is then mixed with mRNA isolated from the cytoplasm of mouse cells. The image represents an electron micrograph result showing the hybridization of single-stranded DNA and mRNA.
Which nucleic acid is indicated by the 'b' pointer? Justify your answer.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
10. Transcription
Transcription in Eukaryotes
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Which of the following modifications occurs to the RNA polymerase tail in order to trigger it to elongate the transcript?
A
Methylation
B
Acetylation
C
Carboxylation
D
Phosphorylation

1
Understand the role of RNA polymerase in transcription: RNA polymerase is an enzyme responsible for synthesizing RNA from a DNA template during the process of transcription.
Learn about the structure of RNA polymerase: It has a tail known as the C-terminal domain (CTD), which plays a crucial role in the regulation of transcription.
Explore the concept of post-translational modifications: These are chemical changes to a protein after it has been synthesized, which can affect its function.
Identify the specific modification related to transcription elongation: Phosphorylation is the addition of a phosphate group to a protein, which can alter its activity.
Connect phosphorylation to RNA polymerase function: The phosphorylation of the RNA polymerase tail (CTD) is a key modification that triggers the transition from transcription initiation to elongation, allowing the enzyme to proceed with RNA synthesis.
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