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Multiple Choice
Which of the following proteins are responsible for unwinding the DNA double helix for replication?
A
DNA helicases
B
Single stranded binding proteins
C
DNA Topoisomerases
D
Sliding Clamp
Verified step by step guidance
1
Understand the process of DNA replication, which involves the unwinding of the DNA double helix to allow each strand to be copied.
Identify the role of DNA helicases, which are enzymes that unwind the DNA double helix by breaking the hydrogen bonds between the nucleotide base pairs.
Recognize the function of single-stranded binding proteins, which stabilize the unwound DNA strands to prevent them from re-annealing or forming secondary structures.
Consider the role of DNA topoisomerases, which alleviate the torsional strain that builds up ahead of the replication fork due to the unwinding process.
Understand the function of the sliding clamp, which helps to hold the DNA polymerase in place during strand elongation, but does not directly participate in unwinding the DNA.