Small molecules play a crucial role in cell biology, with water and carbon being two of the most significant. Water, often referred to as a universal solvent, is essential because it can dissolve a wide variety of substances, making up about 70% of cell weight. This property is vital for cellular processes, as it allows for the transport of nutrients and waste. Understanding the terms hydrophilic and hydrophobic is important; hydrophilic molecules dissolve in water, while hydrophobic molecules do not. The polar nature of water, characterized by an uneven distribution of charge, leads to cohesive properties that stabilize temperature. This is measured by specific heat, which indicates the amount of heat required to raise the temperature of water by 1 degree Celsius. The high specific heat of water means it can absorb significant amounts of heat without a large change in temperature, contributing to homeostasis in biological systems.
Carbon is another fundamental small molecule in biology, known for its ability to form stable covalent bonds with up to four other atoms, including oxygen, hydrogen, nitrogen, and sulfur. The stability of these bonds can be assessed through bond energy, which is the energy required to break a bond, typically expressed in calories per mole in cell biology. Carbon's versatility allows it to create various configurations, including stereoisomers, which are molecules that have the same chemical formula but differ in the arrangement of atoms. This is particularly relevant for asymmetric carbon atoms, which are bonded to four different groups, leading to non-superimposable mirror images. These stereoisomers are significant in biological systems, influencing the function and behavior of biomolecules.
Additionally, carbon molecules often contain functional groups, which are specific groupings of atoms that impart distinct characteristics and functions to the molecules they are part of. These functional groups are essential for the diverse roles that carbon-based compounds play in cellular processes. Overall, the properties of water and carbon are foundational to understanding the biochemical mechanisms that sustain life.