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Multiple Choice
Which ribosomal site of protein synthesis does the initiator tRNA bind to initiation translation?
A
A site
B
P site
C
E site
Verified step by step guidance
1
Understand the role of tRNA in translation: tRNA molecules are responsible for bringing amino acids to the ribosome during protein synthesis. Each tRNA has an anticodon that pairs with a specific mRNA codon.
Learn about the ribosomal sites: The ribosome has three sites for tRNA binding - the A (aminoacyl) site, the P (peptidyl) site, and the E (exit) site.
Identify the function of each site: The A site is where the incoming aminoacyl-tRNA binds, the P site holds the tRNA with the growing polypeptide chain, and the E site is where the tRNA exits the ribosome after its amino acid has been added to the chain.
Focus on the initiation of translation: During the initiation phase, the small ribosomal subunit binds to the mRNA and the initiator tRNA, which carries methionine, binds to the start codon.
Determine the binding site for the initiator tRNA: The initiator tRNA binds directly to the P site of the ribosome, which is unique to the initiation phase, as it allows the polypeptide chain to start forming from the first amino acid.