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Multiple Choice
Before translation initiation, which subunit of the ribosome is recruited to the mRNA first?
A
Small subunit
B
Large subunit
C
Both subunits are recruited to the mRNA at the same time
Verified step by step guidance
1
Understand the process of translation initiation in eukaryotic cells, which involves the assembly of the ribosome on the mRNA to begin protein synthesis.
Recognize that the ribosome is composed of two subunits: the small subunit and the large subunit.
Learn that during translation initiation, the small ribosomal subunit is the first to bind to the mRNA. This is a critical step in scanning the mRNA for the start codon.
Note that the small subunit, along with initiation factors and the initiator tRNA, forms the pre-initiation complex that scans the mRNA for the AUG start codon.
Once the start codon is recognized, the large ribosomal subunit joins the small subunit to form the complete ribosome, allowing translation to proceed.