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Multiple Choice
Which of the following statements concerning inhibitory synapses (IPSPs) is correct?
A
The postsynaptic membrane becomes less permeable to potassium.
B
The postsynaptic membrane becomes less permeable to sodium.
C
The postsynaptic membrane becomes more permeable to potassium and chloride.
D
The permeability of the postsynaptic membrane to sodium, potassium, and chloride is not changed.
E
Channels allow both sodium and potassium ions to diffuse simultaneously through the membrane.
Verified step by step guidance
1
Understand that an inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.
Recognize that IPSPs typically involve the movement of ions that make the inside of the cell more negative, thus hyperpolarizing the membrane.
Identify that the movement of potassium (K+) out of the cell or chloride (Cl-) into the cell can cause hyperpolarization, as both increase the negative charge inside the neuron.
Evaluate the given options: Increased permeability to potassium and chloride ions would lead to hyperpolarization, which is characteristic of an IPSP.
Conclude that the correct statement is: 'The postsynaptic membrane becomes more permeable to potassium and chloride,' as this aligns with the mechanism of IPSPs.