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Multiple Choice
The release of the enzyme metalloproteinase is thought to contribute to the development of __________.
A
bursitis
B
osteoarthritis
C
gout
D
sprains
Verified step by step guidance
1
Begin by understanding what metalloproteinases are. These are enzymes that break down proteins in the extracellular matrix, which is crucial for tissue remodeling and repair.
Consider the role of metalloproteinases in joint health. They are involved in the degradation of cartilage, which is a key component of joints.
Think about conditions that involve the breakdown of cartilage. Osteoarthritis is a condition characterized by the degeneration of cartilage in the joints, leading to pain and stiffness.
Evaluate the options given: bursitis, osteoarthritis, gout, and sprains. Bursitis involves inflammation of the bursae, gout is a type of arthritis caused by uric acid crystals, and sprains are injuries to ligaments. None of these directly involve the enzymatic breakdown of cartilage like osteoarthritis does.
Conclude that the release of metalloproteinases contributes to the development of osteoarthritis due to their role in cartilage degradation.