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Multiple Choice
During presentation of APC-bound antigen, macrophages and dendritic cells secrete the cytokine _____, which activates T helper cells.
A
Interferon.
B
Interleukin-1.
C
Interleukin-2.
D
Histamine.
Verified step by step guidance
1
Understand the role of antigen-presenting cells (APCs) such as macrophages and dendritic cells in the immune response. These cells process and present antigens to T cells, initiating an immune response.
Recognize that cytokines are signaling molecules that mediate and regulate immunity, inflammation, and hematopoiesis. Different cytokines have specific roles in the immune system.
Identify the cytokine that is secreted by macrophages and dendritic cells during the presentation of APC-bound antigens. This cytokine is responsible for activating T helper cells.
Recall that Interleukin-1 (IL-1) is a cytokine produced by activated macrophages and dendritic cells. It plays a crucial role in the activation of T helper cells, promoting their proliferation and differentiation.
Differentiate between Interleukin-1 and other cytokines such as Interleukin-2, Interferon, and Histamine, understanding their distinct functions in the immune response. Interleukin-1 is specifically involved in the activation of T helper cells during antigen presentation.