Multiple Choice
If an effector CD4 cell encounters an antigen presented on a MHC Class II molecule, how would it respond?
21. The Immune System
Major Histocompatibility Complex Molecules
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Once an MHC II molecule on an APC presents an antigen:
A
Effector cells with CD8 markers activate the APC.
B
Effector cells with CD4 kill the APC.
C
Effector cells with CD8 kill the APC.
D
Effector cells with CD4 activate the APC.
Verified step by step guidance1
Understand the role of MHC II molecules: MHC II molecules are found on antigen-presenting cells (APCs) and are responsible for presenting processed antigens to helper T cells.
Identify the type of T cells that interact with MHC II: Helper T cells, which have CD4 markers, recognize antigens presented by MHC II molecules.
Clarify the function of CD4 T cells: CD4 T cells, also known as helper T cells, do not kill cells directly. Instead, they activate other immune cells, including APCs, to enhance the immune response.
Differentiate between CD4 and CD8 T cells: CD8 T cells, also known as cytotoxic T cells, interact with MHC I molecules and are responsible for killing infected or cancerous cells.
Conclude the correct interaction: When an MHC II molecule on an APC presents an antigen, effector cells with CD4 markers (helper T cells) activate the APC, enhancing the immune response.
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