Elise is a 36-year-old woman who has volunteered to donate red bone marrow to a patient in need of a bone marrow transplant for aplastic anemia. The physician performing the bone marrow extraction is an intern, and it is her first time doing the procedure. She asks that you prepare a site on Elise's tibia for the procedure. Is this a good place for red bone marrow to be extracted, considering Elise's age? Why or why not? Can you suggest an alternative location? Explain.

Which of the following is not an anticlotting agent produced by endothelial cells?

a. Prostacyclin

b. Protein C

c. Antithrombin-III

d. Warfarin

Tissue plasminogen activator, urokinase, and plasmin are important components of:

a. coagulation.

b. fibrinolysis.

c. platelet plug formation.

d. hemostasis.

The anticoagulant drug warfarin primarily disrupts the extrinsic/tissue factor coagulation pathway. Explain why disrupting only this pathway disrupts the entire coagulation cascade.

Cirrhosis of the liver often reduces production of many types of plasma proteins, including albumin and clotting factors. Predict the effects on the body of decreased numbers of these proteins in the plasma. Would this also affect the number of γ-globulins in the plasma? Why or why not?

Platelets are similar to erythrocytes in that both structures do not contain a _________________. Platelets are similar to leukocytes in that both their primary functions involve ________________ the body.

Which physiological response causes a reduction in blood flow immediately after a blood vessel injury?

Which of the following statements about vascular spasms is false?

Prostacyclin is a hormone that is normally active in the blood but becomes inactive when a blood vessel ruptures and hemostasis begins. Considering this, which of the following is the most likely function of prostacyclin?