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Multiple Choice
An antibody’s variable region: 1. Varies in amino acid sequence to allow different antibodies to bind different antigens. 2. Is located in the hinge and stem regions of an antibody. 3. Is a portion of the light chain of an antibody. 4. Is a portion of the heavy chain of an antibody.
A
1 & 2.
B
1 & 3.
C
3 & 4.
D
1, 2, & 3.
E
1, 3, & 4.
F
1, 2, 3, & 4.
Verified step by step guidance
1
Understand the structure of an antibody: Antibodies are Y-shaped molecules composed of two heavy chains and two light chains. Each chain has a constant region and a variable region.
Identify the role of the variable region: The variable region of an antibody is responsible for binding to specific antigens. This region varies in amino acid sequence to allow different antibodies to recognize different antigens.
Locate the variable region: The variable region is found at the tips of the Y-shaped structure, which includes parts of both the light and heavy chains, not in the hinge or stem regions.
Analyze the options: Option 1 is correct because the variable region varies in amino acid sequence. Option 3 is correct because the variable region is part of the light chain. Option 4 is correct because the variable region is also part of the heavy chain.
Conclude the correct answer: Based on the analysis, the correct answer is 1, 3, & 4, as these options accurately describe the characteristics and location of the variable region in an antibody.