Multiple Choice
Which of the following cells is capable of specifically responding to a nearly infinite number of epitopes?
21. The Immune System
Review of Cytotoxic vs Helper T Cells
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Helper T cells respond to antigens from _____ and cytotoxic T cells respond to antigens from _____.
A
Macrophages; B cells.
B
Class II MHC; class I MHC.
C
Viruses; bacteria.
D
Class I MHC; class II MHC.
Verified step by step guidance1
Understand the role of Helper T cells and Cytotoxic T cells in the immune response. Helper T cells assist other cells in the immune system, while Cytotoxic T cells directly attack infected cells.
Identify the types of Major Histocompatibility Complex (MHC) molecules: Class I MHC and Class II MHC. Class I MHC molecules present antigens from inside the cell (endogenous), while Class II MHC molecules present antigens from outside the cell (exogenous).
Recognize that Helper T cells (CD4+ T cells) respond to antigens presented by Class II MHC molecules, which are typically found on professional antigen-presenting cells like macrophages, dendritic cells, and B cells.
Understand that Cytotoxic T cells (CD8+ T cells) respond to antigens presented by Class I MHC molecules, which are found on almost all nucleated cells and present antigens from intracellular pathogens like viruses.
Match the correct MHC class to the type of T cell: Helper T cells respond to Class II MHC, and Cytotoxic T cells respond to Class I MHC.
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