Open Question
Predict the effect that tetrodotoxin would have on Albert's muscle fiber action potentials (see question 3). Would it affect end-plate potentials at the motor end plate? Why or why not? (Connects to Chapter 10)
11. Nervous Tissue and Nervous System
Action Potentials
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Casey is taking a new medication that blocks potassium channels. What stage of an action potential would be MOST affected by this drug?
A
The depolarization phase.
B
Reaching threshold.
C
The repolarization phase.
Verified step by step guidance1
Understand the stages of an action potential: An action potential consists of depolarization, repolarization, and hyperpolarization phases.
Depolarization phase: This is when sodium channels open, allowing Na+ ions to enter the neuron, making the inside more positive.
Reaching threshold: This is the point at which the neuron becomes sufficiently depolarized to trigger an action potential.
Repolarization phase: This occurs when potassium channels open, allowing K+ ions to exit the neuron, restoring the negative charge inside.
Consider the effect of blocking potassium channels: Blocking these channels would most affect the repolarization phase, as it would prevent K+ ions from leaving the neuron, delaying the return to resting potential.
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