21. Aldehydes and Ketones: Nucleophilic Addition

Give the structures of the carbonyl compound and the amine used to form the following imines.

(d)

(e)

(f)

Give the structures of the carbonyl compound and the amine used to form the following imines.

(a)

(b)

(c)

Predict the major products of the following reactions.

(i)

Propose mechanisms for the following reactions.

(f)

Draw structures of the following derivatives.

(g) the (E) isomer of the ethyl imine of propiophenone

Propose mechanisms for the three imine-forming reactions just shown.

Predict the products of the following reactions:

(g)

Draw the product of each of the following reactions:

d.

Give the expected products of the following acid-catalyzed reactions.

(d) cyclohexanone + piperidine

Give the expected products of the following acid-catalyzed reactions.

(c) cyclohexanone + aniline

Give the expected products of the following acid-catalyzed reactions.

(b) acetophenone + dimethylamine

Give the expected products of the following acid-catalyzed reactions.

(a) acetophenone + methylamine

Propose a mechanism for the acid-catalyzed reaction of cyclohexanone with pyrrolidine.

Which of the following amino acid side chains can form an imine with a substrate?

Propose a mechanism for each of the following reactions:

b.