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Organic Chemistry 1 Midterm - Part 2 of 3
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4. Alkanes and Cycloalkanes / A-Values / Problem 21
Problem 21

When a substituent moves from the equatorial to the axial position in a chair-chair interconversion, its A value corresponds to its ∆G°value. A values are always positive numbers because most substituents prefer to be in the equatorial position. Calculate ∆G° and Keq for the chair-chair interconversions below using the given A value.


Diagram showing chair-chair interconversion of cyclohexane with a methyl group, A-value: 1.7 kcal/mol.

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