Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.
c. Write the three-letter symbols for the amino acids that would go into the peptide from the mRNA you wrote in part b.

Question

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.

c. Write the three-letter symbols for the amino acids that would go into the peptide from the mRNA you wrote in part b.

Accepted Answer

All right. Hello everyone. So this question says that a certain section of the DNA sequence which is shown here experiences mutation in which the cytosine in the sixth base is replaced by gui write the three letter symbols for the amino acids that would go into the peptide from the MRN A that is translated from the mutated DNA. And here we have four different answer choices labeled A through D proposing a sequence of different amino acids or sequences of different amino acids. So this question isn't actually the most straightforward, right? Because recall at first DNA, which is what we're given is converted into RN A. And then from there that RN A is converted into a protein. So before we can go ahead and figure out the sequence of amino acids that is part of the protein, we have to figure out the RN A first. And before that, we also have to account for the mutation. So let me start by writing the original sequence of DNA just to keep track of everything, right? The original DNA sequence is CAA T AC G AC TG A. And so the mutation is on base number six So we have 123456 and this cytosine is replaced with guanine. So after accounting for the mutation, the sequence is CAA tag G AC TG A. So from here, now we can move forward, right? And now we can account for the MRN A sequence. So to transcribe the mutated DNA sequence into MRN A, we have to recall our complementary base pairing rules, right? When it comes to RN A, adenine would pair with uracil and not finding cytosine would pair with guanine and vice versa. But because we are starting with DNA, a thymine residue or a thymine base, excuse me, on DNA would pair with adenine in the MRN A. So applying these rules, right? For example, the first nucleotide in DNA is cytosine. So guanine would be the first base in the MRN A after that is two adenine. So that's two uracil and then we have one thymine in our DNA strand which would give an adenine in our MRN A. After that, we have a different another adenine. So that's another year or so. And then after that, we have two guanines. So that's two cyto zines in the MRN A another year or so because there's an adenine followed by Guan adenine once more cytosine and uracil. So just to put everything together, our Mrna sequence is Guaucug ac. And so now we can go about converting this MRN a sequence into the amino acid sequence. So I'm just writing a a for short. So at this point, this strand or excuse me, this part is encompassing the translation process, right, in which we're converting MRN A into an amino acid sequence. But before we do that, recall, the translation is done in coda, right? So codons are groups of three nucleotides in the MRN A that each code for an amino acid, either one amino acid or a start stop signal. So here using the genetic code table, we can match each code on in the MRN A, each triplet of nucleotides into the corresponding amino acid or start stop signal. But in this case, they're all coding for amino acids. Our first code on, for example, guu will code for valle. So that's va L thats the three letter abbreviation. Our second code on is A U which codes for isoleucine. So that's Ile. After that, we have cug which is lucine. So that's L eu and then after that, we have AC U, that's our last code on which represents three names. So that's T hr and there you have it. So from there we have our amino acid sequence. So it's veen isoleucine, leucine and threne, which means that our correct answer is option C and so with that being said, thank you so very much for watching. And I hope you found this helpful

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.
c. Write the three-letter symbols for the amino acids that would go into the peptide from the mRNA you wrote in part b.

Verified video answer for a similar problem:

Key Concepts

DNA Mutation

Transcription and mRNA

Amino Acid Codons

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.c. Write the three-letter symbols for the amino acids that would go into the peptide from the mRNA you wrote in part b.

Verified video answer for a similar problem:

Key Concepts

DNA Mutation

Transcription and mRNA

Amino Acid Codons

Suppose a mutation occurs in the DNA section in problem 17.89, and the first base in the parent chain, adenine, is replaced by guanine.
c. Write the three-letter symbols for the amino acids that would go into the peptide from the mRNA you wrote in part b.