The two gels illustrated contain dideoxynucleotide DNA-sequencing information for a wild-type segment and mutant segment of DNA corresponding to the N-terminal end of a protein. The start codon and the next five codons are sequenced.
What is the cause of the mutation?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
17. Mutation, Repair, and Recombination
Types of Mutations
Struggling with Genetics?
Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Changes in the codon reading frame can be caused from all but which of the following?
A
Frameshift mutations
B
Insertions
C
Deletions
D
Missense mutations

1
Understand the concept of a codon reading frame: In genetics, the reading frame refers to the way nucleotides in mRNA are grouped into codons, each consisting of three nucleotides, which are then translated into amino acids.
Recognize what frameshift mutations are: Frameshift mutations occur when nucleotides are inserted or deleted from the DNA sequence, altering the reading frame and potentially changing every subsequent amino acid in the sequence.
Identify the impact of insertions and deletions: Both insertions and deletions can cause frameshift mutations, as they change the number of nucleotides in the sequence, disrupting the grouping of nucleotides into codons.
Clarify what missense mutations are: Missense mutations result in a single nucleotide change that leads to the substitution of one amino acid for another in the protein sequence, but they do not alter the reading frame.
Conclude why missense mutations do not cause changes in the reading frame: Since missense mutations only affect one codon and do not add or remove nucleotides, they do not shift the reading frame, unlike frameshift mutations, insertions, and deletions.
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Types of Mutations practice set
