Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
14. Genetic Control of Development
Developmental Patterning Genes
Struggling with Genetics?
Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Activation of the segmentation genes occurs in which of the following orders?
A
Maternal effect → gap → segment polarity → pair rule
B
Gap → maternal effect → pair rule → segment polarity
C
Maternal effect → gap → pair rule → segment polarity
D
Segment polarity → pair rule → gap → maternal effect

1
Understand the role of maternal effect genes: These genes are expressed by the mother and deposited in the egg, setting up initial conditions for embryonic development.
Learn about gap genes: These are the first zygotic genes activated after maternal effect genes. They define broad regions of the embryo and are crucial for establishing the main body axes.
Explore pair rule genes: These genes are activated after gap genes and are responsible for defining the segmented pattern of the embryo by dividing it into repeating units.
Investigate segment polarity genes: These genes are activated last and refine the segment boundaries established by pair rule genes, ensuring proper segment formation.
Review the correct sequence of activation: Maternal effect genes initiate the process, followed by gap genes, then pair rule genes, and finally segment polarity genes, which is crucial for proper segmentation during embryonic development.
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Open Question
In Drosophila, recessive mutations in the fruitless gene (fru) result in males courting other males; and recessive mutations in the Antennapedia gene (Ant⁻) lead to defects in the body plan, specifically in the thoracic region of the body, where mutants fail to develop legs. The two genes map 15 cM apart on chromosome 3. You have isolated a new dominant Antdᵈ mutant allele that you induced by treating your flies with X-rays. Your new mutant has legs developing instead of antennae on the head of the fly. You cross your newly induced dominant Antᵈ mutant (a pure-breeding line) with a homozygous recessive fru mutant (which is homozygous wild type at the Ant⁺ locus), as diagrammed below:Your cross results in the following phenotypic proportions:Legs on head, normal courting behavior 75Normal head, abnormal courting behavior 25Legs on head, abnormal courting behavior 0Normal head, normal courting behavior 0Provide a genetic explanation for these results and describe a test for your hypothesis
Developmental Patterning Genes practice set
