Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
14. Genetic Control of Development
Developmental Patterning Genes
Struggling with Genetics?
Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Which of the following HOX clusters are responsible for forming the abdominal in Drosophila development?
A
Segment polarity
B
Antennapedia
C
Bithorax
D
Pair rule

1
Understand the role of HOX genes: HOX genes are a group of related genes that control the body plan of an embryo along the head-tail axis. In Drosophila, these genes are organized into clusters that specify the identity of segments.
Identify the HOX clusters: In Drosophila, there are two main HOX gene clusters, Antennapedia and Bithorax. Each cluster is responsible for different parts of the body.
Focus on the Bithorax complex: The Bithorax complex is responsible for the development of the posterior segments, including the abdomen. It includes genes such as Ultrabithorax (Ubx), abdominal-A (abd-A), and Abdominal-B (Abd-B).
Differentiate from other gene types: Segment polarity genes and pair rule genes are involved in earlier stages of segmentation and patterning, not specifically in forming the abdominal segments.
Conclude the role of Bithorax: Recognize that the Bithorax complex is crucial for specifying the identity and development of the abdominal segments in Drosophila.
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Open Question
In Drosophila, recessive mutations in the fruitless gene (fru) result in males courting other males; and recessive mutations in the Antennapedia gene (Ant⁻) lead to defects in the body plan, specifically in the thoracic region of the body, where mutants fail to develop legs. The two genes map 15 cM apart on chromosome 3. You have isolated a new dominant Antdᵈ mutant allele that you induced by treating your flies with X-rays. Your new mutant has legs developing instead of antennae on the head of the fly. You cross your newly induced dominant Antᵈ mutant (a pure-breeding line) with a homozygous recessive fru mutant (which is homozygous wild type at the Ant⁺ locus), as diagrammed below:What phenotypes, and in what proportions, do you expect in the F₂ obtained by interbreeding F₁ animals?
Developmental Patterning Genes practice set
