For the following crosses, determine as accurately as possible the genotypes of each parent, the parent in whom nondisjunction occurs, and whether nondisjunction takes place in the first or second meiotic division. Both color blindness and hemophilia, a blood-clotting disorder, are X-linked recessive traits. In each case, assume the parents have normal karyotypes (see Table 10.2).
A color-blind man and a woman who is wild type have a daughter with Turner syndrome (XO) who has normal color vision and blood clotting.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
6. Chromosomal Variation
Chromosomal Mutations: Aneuploidy
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
True or False:Aneuploids are more abnormal that polyploids
A
True
B
False

1
Understand the definitions: Aneuploids are organisms with an abnormal number of chromosomes, typically missing or having extra chromosomes. Polyploids have more than two complete sets of chromosomes.
Consider the effects of aneuploidy: Aneuploidy often leads to significant developmental abnormalities because the balance of gene expression is disrupted.
Consider the effects of polyploidy: Polyploidy can sometimes be tolerated in organisms, especially plants, and may not result in as severe abnormalities as aneuploidy.
Compare the severity: Aneuploidy tends to cause more severe abnormalities than polyploidy due to the imbalance in chromosome number affecting gene dosage.
Conclude based on comparison: Given the definitions and effects, aneuploids are generally considered more abnormal than polyploids.
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Chromosomal Mutations: Aneuploidy practice set
