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Isoginkgetin is a cell-permeable chemical isolated from the Ginkgo biloba tree that binds to and inhibits snRNPs.
What types of problems would you anticipate in cells treated with isoginkgetin?
10. Transcription
RNA Modification and Processing
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After transcription the RNA sequence cannot be changed or modified before translation.
A
True
B
False
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Understand the central dogma of molecular biology, which describes the flow of genetic information from DNA to RNA to protein. This involves two main processes: transcription and translation.
Recognize that transcription is the process where a segment of DNA is copied into RNA, specifically messenger RNA (mRNA), by the enzyme RNA polymerase.
Learn about RNA processing, which occurs in eukaryotic cells after transcription and before translation. This includes modifications such as 5' capping, 3' polyadenylation, and splicing.
5' capping involves the addition of a modified guanine nucleotide to the 5' end of the mRNA, which is crucial for mRNA stability and initiation of translation.
Splicing is the process where introns (non-coding regions) are removed from the pre-mRNA, and exons (coding regions) are joined together to form a mature mRNA sequence that can be translated into a protein.
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