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Multiple Choice
Which of the following molecules removes phosphates from PI-3 kinase?
A
Phospholipase C
B
Phosphatidylinositol-3 kinase
C
PTEN Phosphatase
D
Protein Kinase C
Verified step by step guidance
1
Understand the role of PI-3 kinase: PI-3 kinase is an enzyme that phosphorylates the 3' position of the inositol ring of phosphatidylinositol lipids, which is a crucial step in cell signaling pathways.
Identify the function of PTEN Phosphatase: PTEN (Phosphatase and Tensin Homolog) is a phosphatase enzyme that specifically removes phosphate groups from the 3' position of the inositol ring, counteracting the action of PI-3 kinase.
Differentiate between kinases and phosphatases: Kinases add phosphate groups to molecules, while phosphatases remove them. This distinction is key to understanding their roles in signaling pathways.
Evaluate the options: Phospholipase C and Protein Kinase C are involved in different signaling pathways and do not remove phosphates from PI-3 kinase products. Phosphatidylinositol-3 kinase is the enzyme that adds phosphates, not removes them.
Conclude with the correct answer: PTEN Phosphatase is the enzyme that removes phosphates from the products of PI-3 kinase, thus regulating the signaling pathway.