Multiple Choice
What is the name of the region on a protein that controls its degradation over time?
7. Gene Expression
Post-Transcriptional Regulators
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What is the name of the enzyme that cleaves the miRNA in the nucleus before it travels to the cytoplasm to exert its effects?
A
RISC
B
Argonaut
C
DROSHA
D
RNA Polymerase
Verified step by step guidance1
Understand the role of miRNA (microRNA) in gene regulation, which involves processing steps in both the nucleus and the cytoplasm.
Recognize that miRNA is initially transcribed as a primary miRNA (pri-miRNA) in the nucleus.
Identify that the pri-miRNA needs to be processed into a precursor miRNA (pre-miRNA) before it can be exported to the cytoplasm.
Learn that the enzyme responsible for cleaving the pri-miRNA into pre-miRNA in the nucleus is called DROSHA.
Note that DROSHA is part of a microprocessor complex that includes other proteins, and this processing is crucial for the miRNA to eventually form a mature miRNA in the cytoplasm.
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