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Multiple Choice
Which of the following is NOT a function of S-Cdks?
A
Causing the entrance of the cell into S phase
B
Recruiting DNA helicases
C
Activating mitogens
D
Promoting the formation of the replication fork
Verified step by step guidance
1
Understand the role of S-Cdks (S-phase Cyclin-dependent kinases) in the cell cycle. S-Cdks are crucial for initiating the S phase, where DNA replication occurs.
Recognize that S-Cdks are involved in the activation of DNA replication machinery. This includes recruiting DNA helicases, which are enzymes that unwind the DNA double helix, allowing replication to proceed.
Identify that S-Cdks promote the formation of the replication fork, a structure that forms at the origin of replication and is essential for DNA synthesis.
Consider the role of mitogens, which are signaling molecules that stimulate cell division by activating pathways that lead to cell cycle progression. Mitogens typically act before the S phase, during the G1 phase, to promote the transition to the S phase.
Conclude that activating mitogens is not a direct function of S-Cdks, as mitogens are involved earlier in the cell cycle to trigger the initial steps leading to S phase entry, rather than being a function of S-Cdks themselves.