Multiple Choice
Which of the following is not a common example of protein kinase signaling cascades?
14. Cell Signaling
Protein Kinase Receptors
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Ligand binding to a receptor kinase causes what to happen?
A
Immediate activation of the single receptor kinase
B
Dimerization and inactivation of two receptor kinases
C
Dimerization and activation of two receptor kinases
D
Binding of the kinase to the receptor
Verified step by step guidance1
Understand the role of receptor kinases: Receptor kinases are proteins that span the cell membrane and play a crucial role in signal transduction by transferring signals from the outside to the inside of the cell.
Recognize the process of ligand binding: A ligand is a molecule that binds specifically to a receptor site of another molecule. In this context, the ligand binds to the receptor kinase.
Identify the effect of ligand binding: When a ligand binds to a receptor kinase, it typically causes the receptor to undergo a conformational change.
Explain dimerization: Dimerization refers to the process where two receptor kinases pair up or 'dimerize' upon ligand binding. This is a common mechanism for receptor activation.
Clarify the activation process: Once dimerized, the receptor kinases activate each other through phosphorylation, a process where a phosphate group is added, leading to the activation of downstream signaling pathways.
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