Multiple Choice
Which of the following is not a form of epigenetic heredity?
7. Gene Expression
Epigenetic Regulation of Gene Expression
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CpG islands are groupings of CG nucleotides that are unusual because why?
A
They are highly methylated
B
They are unmethylated
C
The are found in genes
D
They are highly acetylated
Verified step by step guidance1
Understand the concept of CpG islands: CpG islands are regions of DNA where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction. These regions are often found near or within the promoter regions of genes.
Recognize the significance of methylation: In the context of DNA, methylation typically occurs at the cytosine base of a CpG dinucleotide. Methylation can affect gene expression, often leading to gene silencing.
Identify the typical methylation status of CpG islands: Unlike other CpG sites in the genome, CpG islands are usually unmethylated. This lack of methylation is important for the regulation of gene expression, particularly in housekeeping genes that need to be constantly active.
Consider the options given: The problem provides several statements about CpG islands. Evaluate each statement based on your understanding of their characteristics.
Conclude with the correct characteristic: Based on the typical features of CpG islands, the correct statement is that they are 'unmethylated', which is unusual compared to other CpG sites in the genome that are often methylated.
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