Name the metabolic substrate(s) that can be produced from the carbon atoms of each of the following amino acids:
c. valine

Question

Name the metabolic substrate(s) that can be produced from the carbon atoms of each of the following amino acids:

c. valine

Accepted Answer

All right. Hello everyone. So this question is asking us to determine the metabolic substrate formed using the carbon atoms of searing. And here for our reference is the structure of the amino acids. So here we're talking about the metabolism of an individual amino acid. And so the question is, what is or what are the possible fates of an amino acid in our various metabolic pathways? Well, siren specifically can do a few different things. First of all, serene could enter pathways of gluconeogenesis, which is the synthesis of glucose. But on the other hand, c can be converted into intermediates or specifically one intermediate of the citric acid cycle, which therefore contribute to the production of A TP. So sir, in particular, the key reaction of sine in particular is known as de emanation and deaminate is done by an enzyme known as sine deaminase. So why is that? How do we know that? Well, recall that deaminate is first of all a well known reaction for amino acids, but it's especially common in amino acids like sine that contain hydroxy groups in their side chains. So that's one reason. And what's also worth mentioning is that by removing the amino group of sine sine is converted into a very, very important intermediate of various metabolic pathways for energy production. So what does the demin of Syria look like? Well, first of all, the phrase de emanation implies that the amino group is going to be removed, which is accurate. And in addition to that the skeleton of seine undergoes rearrangement to result in a car bal inside of the carbon chain. So a ketone. So here this is going to erase my backbone. So let me just go ahead and fix that right. We have three carbons in searing in total. So the hydroxy group was previously at the very end of the carbon chain. But Cine deaminase is going to catalyze the rearrangement of that oxygen into a car bal on carbon number two of the chain. So I'm actually going to go ahead and erase the label because this product is no longer searing, right? Instead, if you recall, this compound is actually pyruvate, which is the answer to this question. So Cine is converted into pyruvate, which then can participate in various different metabolic pathways and there you have it. So with that being said, thank you so very much for watching and I hope you found this helpful

Name the metabolic substrate(s) that can be produced from the carbon atoms of each of the following amino acids:
c. valine

Verified video answer for a similar problem:

Key Concepts

Amino Acid Metabolism

Valine Catabolism

Metabolic Substrates

Name the metabolic substrate(s) that can be produced from the carbon atoms of each of the following amino acids:c. valine

Verified video answer for a similar problem:

Key Concepts

Amino Acid Metabolism

Valine Catabolism

Metabolic Substrates

Name the metabolic substrate(s) that can be produced from the carbon atoms of each of the following amino acids:
c. valine