Open QuestionDNA polymerase III is the main DNA-synthesizing enzyme in bacteria. Describe how it carries out its role of elongating a strand of DNA.
Open QuestionKornberg showed that nucleotides are added to the 3' end of each growing DNA strand. In what way does an exposed 3'-OH group participate in strand elongation?
Open QuestionA sample of double-stranded DNA is found to contain 20% cytosine. Determine the percentage of the three other DNA nucleotides in the sample.
Open QuestionList and describe the function of the ten subunits constituting DNA polymerase III. Distinguish between the holoenzyme and the core enzyme.
Open QuestionBacterial DNA polymerase I and DNA polymerase III perform different functions during DNA replication.If a strain of E. coli acquired a mutation that inactivated DNA polymerase III function, would the cell be able to replicate its DNA? Why or why not?
Open QuestionBacterial DNA polymerase I and DNA polymerase III perform different functions during DNA replication.Identify the principal functions of each molecule.