Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
4. Genetic Mapping and Linkage
Mapping Genes
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DNA sequences for 10 individuals are
Nucleotide Position
1 5 10
Person 1 ...GACCTATTGC...
Person 2 ...GAACTATTGC...
Person 3 ...GACCTTTTGC...
Person 4 ...GACCTATTGC...
Person 5 ...CAACTATTGC...
Person 6 ...GACCTTTTGC...
Person 7 ...CAACTATTGC...
Person 8 ...GACCTATTGC...
Person 9 ...CAACTATTGC...
Person 10 ...GAACTATTGC...
Identify the nucleotide positions of all SNPs (single nucleotide polymorphisms).

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In Drosophila, a female fly is heterozygous for three mutations, Bar eyes (B), miniature wings (m), and ebony body (e). Note that Bar is a dominant mutation. The fly is crossed to a male with normal eyes, miniature wings, and ebony body. The results of the cross are as follows.111 miniature 101 Bar, ebony29 wild type 31 Bar, miniature, ebony117 Bar 35 ebony26 Bar, miniature 115 miniature, ebonyInterpret the results of this cross. If you conclude that linkage is involved between any of the genes, determine the map distance(s) between them.