For the sequences given in the following list, indicate whether DNA replication, transcription, pre-mRNA processing, or translation will be most immediately affected by deletion of the sequence. As precisely as you can, specify what step of the process is directly affected by the deletion.
a. start codon
b. TATA box
c. 5' splice site
d. ori sequence
e. -10 consensus sequence
f. Shine–Dalgarno sequence
g. 5' cap
h. termination sequence
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
Translation
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Which of the following represents the wobble hypothesis?
A
CUC and CUA encode for different amino acids
B
CUC and CUU encode for the same amino acid
C
tRNA is specific for only one codon
D
CUC and CUG encode for stop codons

1
Understand the wobble hypothesis: It explains how a single tRNA can recognize multiple codons that differ in their third nucleotide position.
Recall that the genetic code is degenerate, meaning multiple codons can encode the same amino acid.
Identify that the wobble position is the third nucleotide in the codon, which allows for flexibility in base pairing.
Recognize that the wobble hypothesis allows for certain codons, like CUC and CUU, to encode the same amino acid due to this flexibility.
Conclude that the statement 'CUC and CUU encode for the same amino acid' aligns with the wobble hypothesis, as it demonstrates the concept of codon recognition by tRNA despite differences in the third position.
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