Alleles A and a are on one pair of autosomes, and alleles B and b are on a separate pair of autosomes. Does crossover between one pair of homologs affect the expected proportions of gamete genotypes? Why or why not? Does crossover between both pairs of chromosomes affect the expected gamete proportions? Why or why not?

Explain why a 50 percent recovery of single-crossover products is the upper limit, even when crossing over always occurs between two linked genes?

Why are double-crossover events expected less frequently than single-crossover events?

What is the proposed basis for positive interference?

What two essential criteria must be met in order to execute a successful mapping cross?

Two different female Drosophila were isolated, each heterozygous for the autosomally linked genes b (black body), d (dachs tarsus), and c (curved wings). These genes are in the order d–b–c, with b being closer to d than to c. Shown here is the genotypic arrangement for each female along with the various gametes formed by both:Identify which categories are noncrossovers (NCOs), single crossovers (SCOs), and double crossovers (DCOs) in each case. Then, indicate the relative frequency in which each will be produced.

In Drosophila, two mutations, Stubble (Sb) and curled (cu), are linked on chromosome III. Stubble is a dominant gene that is lethal in a homozygous state, and curled is a recessive gene. If a female of the genotypeis to be mated to detect recombinants among her offspring, what male genotype would you choose as a mate?

If the cross described in Problem 18 were made, and if Sb and cu are 8.2 map units apart on chromosome III, and if 1000 offspring were recovered, what would be the outcome of the cross, assuming that equal numbers of males and females were observed?