Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

15. Genomes and Genomics

Sequencing the Genome

Genetics

15. Genomes and Genomics

Sequencing the Genome

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Multiple Choice

The purpose of a sequence assembly is to what?

Use reads to build a conserved sequence

Use reads to build a consensus sequence

Use reads to form a vector

Use reads to form a labeled sequence

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Verified step by step guidance

Understand the concept of sequence assembly: Sequence assembly is the process of aligning and merging fragments from a longer DNA sequence in order to reconstruct the original sequence.

Recognize the term 'reads': In genetics, 'reads' refer to the short sequences of DNA that are obtained from sequencing technologies.

Identify the goal of sequence assembly: The primary goal is to use these reads to build a consensus sequence, which represents the most likely sequence of the original DNA based on the overlapping reads.

Distinguish between 'consensus sequence' and other terms: A consensus sequence is a sequence derived from the alignment of multiple reads, reflecting the most common nucleotide at each position.

Clarify why other options are incorrect: Forming a vector or a labeled sequence are not the primary objectives of sequence assembly; these tasks are related to other processes in genetic engineering and analysis.

8:55m

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Related Practice

Open Question

Recall that when the HGP was completed, more than 40 percent of the genes identified had unknown functions. The PANTHER database provides access to comprehensive and current functional assignments for human genes (and genes from other species).

Go to http://www.pantherdb.org/data/. In the frame on the left side of the screen locate the 'Quick links' and use the 'Whole genome function views' link to a view of a pie chart of current functional classes for human genes. Mouse over the pie chart to answer these questions. What percentage of human genes encode transcription factors? Cytoskeletal proteins? Transmembrane receptor regulatory/adaptor proteins?