Open QuestionWhat genetic process is occurring in a puff of a polytene chromosome? How do we know this experimentally?
Open QuestionWhy might we predict that the organization of eukaryotic genetic material will be more complex than that of viruses or bacteria?
Open QuestionDescribe the transitions that occur as nucleosomes are coiled and folded, ultimately forming a chromatid.
Open QuestionProvide a comprehensive definition of heterochromatin and list as many examples as you can.
Open QuestionMammals contain a diploid genome consisting of at least 10⁹ bp. If this amount of DNA is present as chromatin fibers, where each group of 200 bp of DNA is combined with 9 histones into a nucleosome and each group of 6 nucleosomes is combined into a solenoid, achieving a final packing ratio of 50, determine (a) the total number of nucleosomes in all fibers, (b) the total number of histone molecules combined with DNA in the diploid genome, and (c) the combined length of all fibers.