Open QuestionContrast the contributions made to an understanding of transformation by Griffith and by Avery and his colleagues.
Open QuestionWhen Avery and his colleagues had obtained what was concluded to be the transforming factor from the IIIS virulent cells, they treated the fraction with proteases, RNase, and DNase, followed in each case by the assay for retention or loss of transforming ability. What were the purpose and results of these experiments? What conclusions were drawn?
Open QuestionGiven the state of knowledge at the time of the Avery, MacLeod, and McCarty experiment, why was it difficult for some scientists to accept that DNA is the carrier of genetic information?
Open QuestionDoes the design of the Hershey–Chase experiment distinguish between DNA and RNA as the molecule serving as the genetic material? Why or why not?
Open QuestionWhat observations are consistent with the conclusion that DNA serves as the genetic material in eukaryotes? List and discuss them.
Open QuestionWhat are the exceptions to the general rule that DNA is the genetic material in all organisms? What evidence supports these exceptions?