Using the genomic libraries in Problem 4, you wish to clone the human gene encoding myostatin, which is expressed only in muscle cells.How frequently will a clone representing myostatin be found in the genomic library made from brain?

You have constructed four different libraries: a genomic library made from DNA isolated from human brain tissue, a genomic library made from DNA isolated from human muscle tissue, a human brain cDNA library, and a human muscle cDNA library.Which of these would have the greatest diversity of sequences?

You have constructed four different libraries: a genomic library made from DNA isolated from human brain tissue, a genomic library made from DNA isolated from human muscle tissue, a human brain cDNA library, and a human muscle cDNA library.Would the sequences contained in each library be expected to overlap completely, partially, or not at all with the sequences present in each of the other libraries?

Using the genomic libraries in Problem 4, you wish to clone the human gene encoding myostatin, which is expressed only in muscle cells.Assuming the human genome is 3x10⁹ and that the average insert size in the genomic libraries is 100 kb, how frequently will a clone representing myostatin be found in the genomic library made from muscle?

Using the genomic libraries in Problem 4, you wish to clone the human gene encoding myostatin, which is expressed only in muscle cells.How frequently will a clone representing myostatin be found in the cDNA library made from muscle?

Using the genomic libraries in Problem 4, you wish to clone the human gene encoding myostatin, which is expressed only in muscle cells.How frequently will a clone representing myostatin be found in the cDNA library made from brain?

A victim of murder is found to have scrapings containing skin cells under several of her fingernails. Genetic analysis confirms that the DNA isolated from these cells came from the same individual and does not match the DNA of the victim. The results shown below are for six CODIS STR markers from the crime scene DNA (from under the victim's fingernails and presumed to be the murderer's), and from three suspects (A, B, and C) who have been detained for questioning about the murder.Is there a failure to exclude any of the suspects? Explain.

A victim of murder is found to have scrapings containing skin cells under several of her fingernails. Genetic analysis confirms that the DNA isolated from these cells came from the same individual and does not match the DNA of the victim. The results shown below are for six CODIS STR markers from the crime scene DNA (from under the victim's fingernails and presumed to be the murderer's), and from three suspects (A, B, and C) who have been detained for questioning about the murder.Do the STR results exclude any of the three suspects? Explain.