How would mutations that inactivate each of the following genes a...

Question

How would mutations that inactivate each of the following genes affect the determination of the lytic or lysogenic life cycle in mutated λ phage strains? Explain your answers.int

Accepted Answer

Hey, everyone. Let's take a look at this question together which of the following gene expression will be indirectly affected as a result of a mutation in the int gene. Is it answer choice. A the CLL gene, answer choice B the or one gene, answer choice C the CL gene or answer choice D the cro gene. Let's work this problem out together to try to figure out which of the following genes will be indirectly affected as a result of a mutation in the int gene. So we know that if we have a mutation in the int gene, so we have that mutation NV int gene, it would result in the prevention of the activation of the PR promoter, which an inactivated PR promoter would reduce the levels of the CL protein. And reduce levels of that protein means that we have decreased levels of the CLG. Since higher levels of that CL protein means that we have higher levels of the CL gene. So a reduction of the levels of the protein means a reduction of the levels of the genes as well. So we have a decrease in the expression of that CL gene which results in an increase in the expression of the lytic genes. Since the cl genes and the lytic genes are inversely related and a decrease in the expression of the CL gene causes that increase in the expression of the lytic genes. And so we know that mutation in the int gene would result in those decreased levels of the CL gene making answer choice. C the correct answer since that mutation in the int gene would indirectly affect the CL gene by preventing that activation of the pr promoter, reducing the levels of the CL protein leading to a decrease in the expression of the CL gene. So answer choice C is the correct answer. I hope you found this video to be helpful. Thank you and goodbye.

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How would mutations that inactivate each of the following genes affect the determination of the lytic or lysogenic life cycle in mutated λ phage strains? Explain your answers.int

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