A woman with severe discoloration of her tooth enamel has four children with a man who has normal tooth enamel. Two of the children, a boy (B) and a girl (G), have discolored enamel. Each has a mate with normal tooth enamel and produces several children. G has six children—four boys and two girls. Two of her boys and one of her girls have discolored enamel. B has seven children—four girls and three boys. All four of his daughters have discolored enamel, but all his boys have normal enamel. Explain the inheritance of this condition.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Monohybrid Cross
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In cats, tortoiseshell coat color appears in females. A tortoiseshell coat has patches of dark brown fur and patches of orange fur that each in total cover about half the body but have a unique pattern in each female. Male cats can be either dark brown or orange, but a male cat with tortoiseshell coat is rarely produced. Two sample crosses between males and females from pure-breeding lines produced the tortoiseshell females shown.
Cross I P: dark brown male × orange female
F₁: orange males and tortoiseshell females
Cross II P: orange male × dark brown female
F₁: dark brown males and tortoiseshell females
Explain the inheritance of dark brown, orange, and tortoiseshell coat colors in cats.

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Monohybrid Cross practice set
