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Ch.16 - Acid-Base Equilibria
Chapter 16, Problem 111

Ritalin is the trade name of a drug, methylphenidate, usedto treat attention-deficit/hyperactivity disorder in youngadults. The chemical structure of methylphenidate isChemical structure of ibuprofen, a common pain reliever.
(a) Is Ritalin an acid or a base? An electrolyte or a nonelectrolyte?

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1
Step 1: Identify the functional groups in the chemical structure of methylphenidate. Look for groups that can donate or accept protons (H+).
Step 2: Determine if the molecule has any acidic or basic functional groups. Acids typically have carboxyl groups (-COOH), while bases often have amine groups (-NH2).
Step 3: Assess the molecule's ability to dissociate in water. Electrolytes dissociate into ions in water, while nonelectrolytes do not.
Step 4: Compare the structure of methylphenidate to known acids, bases, electrolytes, and nonelectrolytes to make an informed decision.
Step 5: Conclude whether Ritalin (methylphenidate) is an acid or a base, and whether it is an electrolyte or a nonelectrolyte based on the functional groups and dissociation properties.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Acids and Bases

Acids are substances that can donate protons (H+) in a solution, while bases can accept protons. The strength of an acid or base is determined by its ability to dissociate in water. Understanding whether a compound behaves as an acid or a base is crucial for predicting its reactivity and interactions in biological systems.
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Electrolytes

Electrolytes are substances that dissociate into ions when dissolved in water, allowing the solution to conduct electricity. Strong electrolytes completely dissociate, while weak electrolytes partially dissociate. Identifying whether a compound is an electrolyte or nonelectrolyte is important for understanding its behavior in physiological conditions and its effects on cellular functions.
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Chemical Structure and Functional Groups

The chemical structure of a compound, including its functional groups, determines its chemical properties and biological activity. For example, the presence of carboxylic acid groups (-COOH) can indicate acidic behavior, while amine groups (-NH2) can suggest basic properties. Analyzing the structure of methylphenidate is essential for determining its classification as an acid or base and its electrolyte nature.
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