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Multiple Choice
In which of the following steps does the cell cross the spindle assembly checkpoint?
A
Prophase
B
Prometaphase
C
Metaphase
D
Anaphase
E
Telophase
Verified step by step guidance
1
Understand the spindle assembly checkpoint: It is a control mechanism that ensures chromosomes are properly attached to the spindle fibers before the cell proceeds with division.
Identify the phases of mitosis: Prophase, Prometaphase, Metaphase, Anaphase, and Telophase.
Recognize that the spindle assembly checkpoint occurs during Metaphase, where the cell checks for proper alignment of chromosomes at the metaphase plate.
During Metaphase, the cell ensures that all chromosomes are correctly attached to the spindle apparatus and aligned at the metaphase plate before proceeding to Anaphase.
Once the checkpoint is passed, the cell can safely proceed to Anaphase, where sister chromatids are separated and pulled towards opposite poles.