Multiple Choice
Under which condition is a GTP cap formed during microtubule formation?
15. Cytoskeleton and Cell Movement
Microtubules
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Treadmilling is when a microtubule end switches from polarization to depolarization.
A
True
B
False
Verified step by step guidance1
Understand the concept of treadmilling: Treadmilling is a dynamic process observed in cytoskeletal filaments like microtubules and actin filaments, where there is a net addition of subunits at one end and a net loss at the other end, maintaining a constant length.
Differentiate between treadmilling and dynamic instability: Dynamic instability refers to the rapid switching between growth and shrinkage at the ends of microtubules, whereas treadmilling involves a steady state where one end grows while the other shrinks.
Clarify the terms polarization and depolarization: In the context of microtubules, polarization refers to the growth or elongation of the microtubule, while depolarization refers to its shortening or shrinkage.
Analyze the statement: The statement suggests that treadmilling involves a switch from polarization to depolarization, which is not accurate. Treadmilling involves simultaneous growth at one end and shrinkage at the other, not a switch between the two states.
Conclude the analysis: Based on the understanding of treadmilling and dynamic instability, the statement is false because treadmilling does not involve a switch from polarization to depolarization, but rather a balance of both processes at opposite ends.
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