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Multiple Choice
Which of the following proteins are associated with actin nucleation?
A
Arp 2/3
B
ADF
C
Profilin
D
Integrin
Verified step by step guidance
1
Understand the role of actin nucleation in the cell. Actin nucleation is the process that initiates the formation of new actin filaments, which are crucial for various cellular functions such as movement and structure.
Identify the proteins listed in the problem: Arp 2/3, ADF, Profilin, and Integrin. Each of these proteins has a specific role in the cell, particularly in relation to actin filaments.
Learn about the Arp 2/3 complex. This protein complex is known to initiate the nucleation of new actin filaments by creating a branch on an existing filament, which is a key step in actin filament network formation.
Examine the roles of ADF (Actin Depolymerizing Factor) and Profilin. ADF is involved in disassembling actin filaments, while Profilin binds to actin monomers and facilitates their addition to the growing end of actin filaments, but neither directly nucleates actin.
Consider the function of Integrin. Integrins are transmembrane receptors that facilitate cell-extracellular matrix adhesion, and they do not play a direct role in actin nucleation.