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Multiple Choice
Which of the following genes normally suppress tumor growth, but when mutated allow for tumor growth?
A
Carcinogens
B
Oncogene
C
Tumor suppressors
D
Proto-oncogenes
Verified step by step guidance
1
Understand the role of tumor suppressor genes: These genes are crucial in regulating cell growth and division. They act as a brake on cell proliferation, ensuring that cells do not divide uncontrollably.
Recognize what happens when tumor suppressor genes are mutated: Mutations in these genes can lead to a loss of function, meaning the 'brake' on cell division is removed, allowing cells to grow and divide unchecked, which can lead to tumor formation.
Differentiate between tumor suppressor genes and oncogenes: Oncogenes are mutated forms of proto-oncogenes, which normally promote cell growth and division. When mutated, oncogenes can lead to excessive cell proliferation.
Identify the correct term: The problem asks for genes that normally suppress tumor growth but allow it when mutated. This description fits tumor suppressor genes, as their normal function is to prevent uncontrolled cell growth.
Conclude with the correct answer: Based on the understanding of the roles and mutations of these genes, the correct answer is 'Tumor suppressors', as they are the ones that suppress tumor growth under normal conditions but can lead to tumor growth when mutated.