Multiple Choice
Which vesicle is responsible for carrying receptors back to the plasma membrane?
13. Intracellular Protein Transport
Endocytic Pathways
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High blood cholesterol develops when what happens to the LDL receptor?
A
Too much LDL receptor is produced
B
Too little LDL receptor is produced
C
LDL binds the LDL receptor
D
The cell takes in too much LDL in clathrin coated pits
Verified step by step guidance1
Understand the role of LDL receptors: LDL receptors are responsible for binding low-density lipoprotein (LDL) particles and facilitating their uptake into cells, primarily in the liver, for cholesterol processing.
Recognize the consequence of reduced LDL receptors: When there are too few LDL receptors, the ability of cells to take up LDL from the bloodstream is diminished, leading to higher levels of LDL cholesterol in the blood.
Consider the impact of high blood cholesterol: Elevated levels of LDL cholesterol in the blood can lead to the development of atherosclerosis, which is the buildup of cholesterol plaques in the walls of arteries.
Differentiate between the options: Too much LDL receptor production would increase LDL uptake, reducing blood cholesterol levels. Conversely, too little LDL receptor production would decrease LDL uptake, increasing blood cholesterol levels.
Conclude with the correct scenario: High blood cholesterol develops when there is insufficient production of LDL receptors, as this leads to reduced clearance of LDL from the bloodstream.
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