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Multiple Choice
Which of the following processes allows for the creation of so many diverse antibodies?
A
V(D)J recombination
B
V(J) recombination
C
Class switching
D
Constant regions
Verified step by step guidance
1
Understand that the immune system needs to produce a vast array of antibodies to recognize and neutralize a wide variety of antigens.
Learn that antibodies are composed of variable (V), diversity (D), and joining (J) gene segments, which can be rearranged to create diverse antigen-binding sites.
Explore the process of V(D)J recombination, which is a mechanism of genetic recombination that occurs in the developing lymphocytes during the early stages of T and B cell maturation.
Recognize that V(D)J recombination involves the random selection and joining of V, D, and J gene segments, leading to the generation of unique variable regions in antibodies.
Note that while class switching and constant regions are important for antibody function and diversity, V(D)J recombination is the primary process responsible for the initial diversity of antibodies.